Acyclovir (Zovirax®)

Purpose:
Acyclovir is used to prevent or treat herpes simplex and shingles. Acyclovir will not get rid of the herpes viruses, but it will lessen the pain and help heal the sores. It may be used to decrease the severity of CMV infections.

How to take:

• Capsules - 200 mg; tablets - 400 mg and 800 mg; liquid - 200 mg per 5 mL; and ointment. If taking Acyclovir by mouth, take it with food to reduce stomach upset.

• The transplant team will determine the proper dosage and length of time to take Acyclovir.

Precautions:

• Keep the affected areas as clean and dry as possible.

• Wear loose-fitting clothing to avoid irritating the infected area and spreading the virus.

• Acyclovir will not prevent herpes from spreading to others. It is best not to have sex if either partner has any symptoms of genital herpes.

• Condoms may help prevent the spread of genital herpes, but vaginal jellies and diaphragms will not.

• Avoid kissing or having oral sex with someone who has a cold sore.

• The benefits of taking Acyclovir if a patient is pregnant or breast feeding must be weighed against the potential hazards to her, her fetus, or her infant. A patient should consult her transplant team immediately if she thinks she's pregnant.

Principal side effects:

These include, but are not limited to, nausea, vomiting, diarrhea, headache, and rash.