Medications and Complications
A Patient's Guide to Kidney Transplant Surgery

INFORMATION ABOUT SPECIFIC MEDICATIONS

Including: infection-fighting drugs, antifungal drugs, drugs that protect the digestive system, and nutritional supplements.


Mycophenolate Mofetil (CellCept)
Fights rejection by decreasing the number of white blood cells the immune system produces. More information

Cyclosporine (Neoral, Sandimune, Cylosporine A, Gengraf)
Used to prevent rejection of a transplanted organ. It is used for long-term (perhaps lifetime) immunosuppression. More information

Medications Tacrolimus (Prograf, FK506)
Tacrolimus is prescribed to prevent or treat organ rejection in people who have received kidney transplants. It is used for long-term (perhaps lifetime) immunosuppression. More information

Prednisone (Deltasone)
Prednisone is a corticosteroid that helps prevent and treat rejection of transplanted organs. It may be used for long-term (perhaps lifetime) immunosuppression or, in higher doses, for treatment of rejection. More information

Azathioprine (Imuran)
Azathioprine is given with other immunosuppressants to help prevent rejection of the new kidney. It may be used for long-term (perhaps lifetime) immunosuppression. More information

Muromonab-CD3 (Orthoclone OKT®3)
Muromonab-CD3 may be given immediately following kidney transplant to prevent rejection. It may also be used to treat rejection. More information

Daclizumab (Zenapax®)
Used in combination with standard immunosuppressive agents. It is the first genetically engineered drug to reduce the risk of organ rejection in kidney transplant patients without increasing overall side effects. More information

INFECTION-FIGHTING DRUGS

Bactrim
Bactrim is used to prevent and treat PCP and other infections. The risk of PCP is increased for transplant patients because of the drugs taken to suppress their immune systems, which reduce their bodies' ability to fight infection. More information

Ganciclovir (Cytovene®)
Ganciclovir is used to prevent or treat cytomegalo virus (CMV) infection. More information

Acyclovir (Zovirax®)
Acyclovir is used to prevent or treat herpes simplex and shingles. Acyclovir will not get rid of the herpes viruses, but it will lessen the pain and help heal the sores. It may be used to decrease the severity of CMV infections. More information

ANTIFUNGAL DRUGS
Various drugs are used to treat or prevent fungus infections. More information

DRUGS THAT PROTECT THE DIGESTIVE SYSTEM
Because some medications can cause ulcers in the stomach and upper intestine, a patient may need to take other medications to help protect the digestive system. These drugs will be prescribed by the transplant team when necessary. More information

NUTRITIONAL SUPPLEMENTS
The transplant team may recommend that a patient take vitamin, iron, magnesium, and/or calcium supplements in case his diet is not providing adequate amounts of the nutrients that is needed.





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If you have any questions, please contact us:
USC Kidney Transplant Program
Phone: (323) 442-5908, Fax: (323) 442-5721
E-mail: usckidney@surgery.hsc.usc.edu